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Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE DNA 62 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCCCC#C)CCN(CC(O)=O)CC1 Purity (HPLC)

SKU 99660184151
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Description

62 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCCCC#C)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

The conjugates of TMR C2 maleimides have the identical excitation and emission wavelengths at 544/572 nm to those of tetramethylrhodamine maleimides or iodoacetamide

609 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCN=[N+]=[N-])CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

84 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCCO)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Thalidomide-O-PEG3-C2-amine HCl Synonyms Thalidomide-4'-O-PEG3-C2-amine HCl CAS Number 2387510-82-7 Related CAS Molecular Formula C21H28ClN3O8 Molecular Weight 485

Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE DNA 62 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCCCC#C)CCN(CC(O)=O)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is

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