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1038/nchembio
Product Name Propargyl-Gly(m-PEG4)-Val-Ala-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C40H65N5O14 Molecular Weight 839
Product Name Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C98H153N13O30 Molecular Weight 1993
making it ideal for aqueous-based applications without requiring organic solvents
S)-AHPC-CO-C5-NH2 HCl Synonyms CAS Number 2415256-20-9 Related CAS 2170695-19-7 (free base) Molecular Formula C28H43Cl2N5O4S Molecular Weight 616
DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE bronic ester 1038/nchembioSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to
