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Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Size:10mg 76 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCC#C)C(C)(C)C)C=C1 Purity (HPLC)

SKU 94019507076
4.5
USD495.00 USD539.00

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Description

76 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCC#C)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

MaP555-Maleimide is a fluorogenic probe

has enhanced potency in PIK3CA mutant models through a unique mechanism of action

Product Name CA-DOTA-tris(t-Bu) Synonyms HaloTag DOTA-tris(t-Bu) Ligand

For research use only

Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Size:10mg 76 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCC#C)C(C)(C)C)C=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The

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