DOTA-C6-propanamido-maleimide crbn 38 SMILES Cl

38 SMILES Cl

NCCCCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

protein misfolding or aggregation disrupts this quenching

NRX-103095 acts as molecular glue in cells to promote the ubiquitylation and subsequent degradation of mutantbeta-catenin by the 26S proteasome

1038/s41467-022-33526-z

DOTA-C6-propanamido-maleimide crbn 38 SMILES ClDOTA bifucational chelator containing a thiol reactive maleimide group, an alkyl linker, and the macrocyclic chelator DOTA ( 1,4,7,10 tetraazacyclododecane 1,4,7,10 tetraacetic acid). It can be used in many different diagnostic and therapeutic applications, such as MRI contrast agents, PET and SPECT imaging agents, and radiotherapeutic agents. Product Name DOTA C6 propanamido maleimide (TFA salt) Synonyms CAS Number n a Related CAS Molecular Formula