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Mal-Propionyl-PEG8-Val-Ala-PAB(m-PEG4)-MMAE Size:5mg 85 SMILES Cl

SKU 8263169872
4.2
USD445.00 USD487.00

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Description

85 SMILES Cl

Product Name Lenalidomide-PEG5-C2-amine HCl Synonyms Lenalidomide-4'-PEG5-C2-amine HCl CAS Number 2138440-77-2 Related CAS Molecular Formula C25H39ClN4O8 Molecular Weight 559

417 SMILES OC(=O)CCOCCOCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name DOTA-tris(t-Bu)ester-propargyl Synonyms CAS Number 911197-00-7 Related CAS Molecular Formula C31H55N5O7 Molecular Weight 609

Product Name tert-butyl 4-(piperazin-1-yl)butanoate Synonyms CAS Number n/a Related CAS Molecular Formula C12H24N2O2 Molecular Weight 228

Mal-Propionyl-PEG8-Val-Ala-PAB(m-PEG4)-MMAE Size:5mg 85 SMILES ClSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly

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