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DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB Size:10mg Product Name BC-Biotin Synonyms Biotin-CLIP

SKU 70725034629
4.6
USD195.00 USD243.00

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Ships within 48 hours · Estimated delivery Aug 15 - Aug 20

Description

Product Name BC-Biotin Synonyms Biotin-CLIP CAS Number Related CAS Molecular Formula C28H39N7O4S Molecular Weight 569

Product Name Mal-Propionyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-PNP Synonyms CAS Number Related CAS Molecular Formula C50H71N7O20 Molecular Weight 1090

Product Name DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C83H102FN11O21 Molecular Weight 1608

987 Purity (HPLC) >= 95% Solubility DMSO

MC-Val-Cit-PABC-PNP is a cathepsin-cleavable ADC linker that connects antibodies to cytotoxic payloads through a Val–Cit peptide and PABC spacer

DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB Size:10mg Product Name BC-Biotin Synonyms Biotin-CLIPSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing

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