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Mal-Acetyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-Exatecan deuterium-labeled-aldehyde it showed no significant change

SKU 64858947727
4.8
EUR445.00 EUR483.00

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Description

it showed no significant change in labeling kinetics

354 SMILES OCCOCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

89 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCCCC#C)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name: 6-FAM alkyne Synonyms: 6-carboxyfluorescein

Product Name Thalidomide-O-acetamido-PEG2-propargyl Synonyms Thalidomide-4'-O-acetamido-PEG2-propargyl CAS Number n/a Related CAS Molecular Formula C22H23N3O8 Molecular Weight 457

Mal-Acetyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-Exatecan deuterium-labeled-aldehyde it showed no significant changeSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,

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