Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE payload 546 Purity (HPLC) >= 95%

546 Purity (HPLC) >= 95% Solubility DMSO

ZXH-1-161 is a potent cereblon (CRBN) modulator with an IC50 value of 39 nM in MM1

SHP099 is a highly potent (IC50 = 0

Product Name 3-{4-[(tert-butoxy)carbonyl]piperazin-1-yl}propanoic acid Synonyms CAS Number 242459-97-8 Related CAS Molecular Formula C12H22N2O4 Molecular Weight 258

where they serve as highly potent cytotoxic payloads

Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE payload 546 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Azide Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further