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Mal-Propionyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan heterocycle NVP-DKY709 acts as a molular

Description

NVP-DKY709 acts as a molular glue that promotes degardation of IKZF2 for the treatment of cancers

Product Name DOTA-PEG6 Synonyms CAS Number n/a Related CAS Molecular Formula C28H53N5O13 Molecular Weight 667

517 Purity (HPLC) >= 95% Solubility DMSO

CA-TMR has been used for tracking protein localization

Product Name Lenalidomide-PEG2-C2-azide Synonyms Lenalidomide-4'-PEG2-C2-azide CAS Number 2399455-48-0 Related CAS Molecular Formula C19H24N6O5 Molecular Weight 416

Mal-Propionyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan heterocycle NVP-DKY709 acts as a molularSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The

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