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Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG4)-PNP acid MaP555-DBCO is is a fluorogenic

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Description

MaP555-DBCO is is a fluorogenic probe

Product Name dCeMM2 Synonyms CAS Number 296771-07-8 Related CAS Molecular Formula C16H11ClN6OS Molecular Weight 370

404 SMILES CN1C(=O)C(C)=C2N(C(=O)N(C3CC3)C(=O)C2=C1NC1=C(F)C=C(I)C=C1)C1=CC(NC(C)=O)=CC=C1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

608 Purity (HPLC) >= 95% Solubility DMSO

emission maximum = 672 nm

Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG4)-PNP acid MaP555-DBCO is is a fluorogenicSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an

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