Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg Product Name Azide-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan Synonyms CAS

Product Name Azide-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C64H87FN12O19 Molecular Weight 1347

785 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name CA-Oregon Green Synonyms Oregon Green-Halo

106 SMILES [2H]C([2H])([2H])NC1=CC=C(Br)C=C1C(=O)OC Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Thalidomide-5'-piperazine-C2-piperazine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C23H33Cl3N6O4 Molecular Weight 563

Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg Product Name Azide-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,