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Isoindole-
Product Name Lenalidomide-C3-acid Synonyms Lenalidomide-4'-C3-acid CAS Number 1781226-49-0 Related CAS Molecular Formula C17H19N3O5 Molecular Weight 345
Product Name Azide-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C44H76N10O15 Molecular Weight 985
Product Name Thalidomide-5'-O-PEG4-propargyl Synonyms CAS Number n/a Related CAS Molecular Formula C24H28N2O9 Molecular Weight 488
1038/s41586-019-1722-1
PC-6 Size:100nmol Isoindole-PC 6 is a specially designed fluorescent probe for detecting SARM1 activity, built by conjugating a styryl donor group to a pyridine acceptor to form a donoracceptor system. It functions through SARM1s base exchange reaction, where PC 6 is converted into a positively charged product (PAD6) upon incorporation into NAD, leading to strong intramolecular charge transfer and a large fluorescence shift (from ~430 nm to ~520 nm). Among a series of related