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It is converted from 6-carboxytetramethylrhodamine (6-TAMRA) and has similar spectroscopic properties of 6-TAMRA
Product Name DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C97H119FN12O27 Molecular Weight 1904
6-TAMRA is the purified single isomer of 5(6)-TAMRA
562 SMILES: OC1=CC2=C(C=C1)C1(OC(=O)C3=CC(=CC=C13)C(=O)NCCOCCOCCOCCN=[N]#N)C1=CC=C(O)C=C1O2
492 SMILES O=C(COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1)NCCOCCOCCOCC#C Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
DBCO-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8) Size:25mg It is converted from 6-carboxytetramethylrhodamineSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be finely tuned through
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