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Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation
Mayasundari
854 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCCN=[N+]=[N-])CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
S)-AHPC-acetamido-O-PEG1-OH Synonyms CAS Number n/a Related CAS Molecular Formula C26H36N4O6S Molecular Weight 532
Beyond monitoring protein aggregation
BG- diAcFAM deuterium-labeled-ketone Discovery of a molecular glueSNAP tag is a self labeling protein derived from human O6 alkylguanine DNA alkyltransferase. At 20 kDa, SNAP tag is smaller than HaloTag (33 kDa), potentially reducing interference with the tagged proteins function. SNAP tag reacts with covalently with benzylguanine (BG)or chloropyrimidine (CP) derivatives, forming a stable thioether bonds that ensures durability for long term experiments or harsh conditions. SNAP tag can be used alongside other tags
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